Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location NCT ID

Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 2)

Systemic Lupus Erythematosus Phase3 Argentina
Australia
Chile
Colombia
France
Germany
India
Italy
Malaysia
Mexico
Romania
South Korea
Taiwan
United Kingdom
United States
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A Prospective NIS to Evaluate the Clinical Outcomes of Risarg® (Ribociclib) Combined With Endocrine Therapy or Chemotherapy in Patients With HR+HER2 - aBC in Routine Clinical Practice in the Russia

HR+HER2- Advanced Breast Cancer Russia

Dabrafenib and/or Trametinib Rollover Study

Melanoma, Non Small Cell Lung Cancer, Solid Tumor, Rare Cancers, High Grade Glioma Phase4 Spain
United States

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

Sickle Cell Disease Phase1, Phase2 United States

A Post Marketing Surveillance on Piqray in Korea

Breast Cancer South Korea

Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

IC-MPGN Phase3 Argentina
Brazil
Canada
France
Germany
Greece
India
Israel
Italy
Japan
Netherlands
Poland
Slovakia
South Korea
Spain
Switzerland
Taiwan
Turkey (Türkiye)
United Kingdom
United States
Vietnam
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A Study of Secukinumab to Evaluate Maintenance of Response in Participants With Non-radiographic Axial Spondyloarthritis Who Achieved Remission

Non-radiographic Axial Spondyloarthritis Phase4 Belgium
Brazil
Colombia
Czechia
France
Germany
Hungary
Israel
Italy
Malaysia
Mexico
Netherlands
Philippines
Poland
Romania
Thailand
Turkey (Türkiye)
Vietnam
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The Belgian REAL (BE.REAL) Registry

Atherosclerotic Cardiovascular Disease Belgium

Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Atypical Hemolytic Uremic Syndrome Phase3 China
France
Germany
Italy
Japan
Spain
Turkey (Türkiye)
United Kingdom
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Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.

Lymphatic Malformations Phase2, Phase3 Australia
Belgium
France
Germany
Italy
Netherlands
Spain
United States
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